I lost a friend to ket. He was partying with bad people, he was sick, choked on his vomit and they stole his stuff / left him to die.
Ketamine is a very interesting ride, and has wonderful potential as an antidepressant, but for the love of yourself (and my badly missed friend, John the magic man), PLEASE have someone compus mentus watching over you while you experience it, if you choose to do so.
Also strongly recommend you DO NOT mix with alcohol.
They gave me ketamine the last time I was in the hospital for pain so they could knock me out.
It was the single worst experience of my life, even worse than the injury I was being knocked out for. I was semi conscious the entire time, but I couldn't feel or hear anything. I just knew people were all around me doing something. It feels like I was dead for a while. I have very few memories from the time they first gave it to me in the ambulance to the time I woke up at home the next day.
Fucking awful experience all around. Next time I was in the hospital for an unrelated condition I told them I'd rather have zero pain medicine than even a tiny amount of ketamine
I think you and I had very different experiences! While ket abuse can defo lead to paranoia and becoming more insular, in my circles it was taken at hard house / trance events or after parties. Lots of silliness and fun times.
Unfortunately for my friend, he lived on his own in Manchester and fell in with a rough crowd after moving to Salford :'(
When Friends was current I wasn't a fan, the small bits I'd seen mostly annoyed me and - disaffected gothy teens/early twenties guy that I was - I dismissed it as one of those things everyone in the mainstream liked and was therefore obviously garbage.
Nowadays I'm married to a Friends fan who has begun showing me the series. As we progress through the box set I'm realizing it's actually pretty good, a couple of the characters actually still annoy me when they're focused on but there's a ton else going on that's pretty entertaining. I'm particularly surprised to be enjoying Chandler so much.
It's very sad what Matthew Perry went through in life and how he died, but I'm now belatedly appreciating some of the work he did.
you can't just do that mate, same with Seinfeld, they were filmed in front of a live audience, they had to stop for laughter otherwise you wouldn't hear what they are saying.
or are you gonna come out and say Seinfeld isn't hilarious?
I'm still not sure I'd call it good, but it was a big step up from sitcoms before it. It tried pretty hard to not be sexist, and introduced some diversity that wasn't just John Ritter pretending to be gay for lulz. It is still spectacularly unrealistic, but whatever. It's a sitcom! It does have some genuinely funny moments.
I still periodically get "Smelly Cat" stuck in my head. Fuck, I'm guilty of making Ross-esque synthesizer music...
Very true. There are also definitely still some 1990s-era LGBTQIA+ phobic jokes which were wrong then and really stick out now, but in general I'd call the writing surprisingly decent.
As a New Yorker, though, I still couldn't afford that apartment in a million years.
Damn, I did not know Ket could depress respiration like this! In fact Ket is used medicinally in place of opioids as it doesn't depress respiration. But here is the TIL part: it should not be mixed with benzos or alcohol (or other depressants I would imagine). I don't use bu I hope someone who does get to read this.
ketamine is anaesthetic and was used in the past in combat medicine and such, because it is quite safe when administered by untrained staff. the fact it is used to treat depression is new to me, but getting in the pool while high on it is the most stupid idea ever :(.
He was in the bathtub and drowned. If you take enough ketamine, it will literally incapacitate you (for many, that's the entire point). He did this in a bathtub.
He did not die from overdosing on ketamine, because that's nearly impossible. He was stupid and incapacitated himself in a bathtub and drowned. It sucks, and it's easy to just blame a chemical.
I'm sure there are people who die after having a couple drinks and getting into the tub, but do we then say that they "died due to the acute effects of alcohol"? No. We say they drowned.
I've been there too. I saw the singularity and touched god... and I'm a goddamn atheist. Coming back from that experience changed me. The memories were fleeting. I couldn't remember the specifics after I returned to baseline. All the knowledge that I was given dissipated... but the overwhelming sense of calm persisted.
Im fairly certain that what I'm about to say will be disliked by ketamine users and abstainers.
Ketamine is garbage at everything besides temporarily lobotomizing people. It works for it's many uses because it makes the user stupid. It's often given to suicidal people, not because it's a miracle drug, but because it incapacitates them in a safe manner.
That said, it's great at making people too stupid to be able to hurt themselves, most of the time. It's great at numbing psychological pain because the user will be too stupid to conceptualize their own thoughts or realize where they are physically.
It's also hard on the urinary system and has a fleeting high.
If you like ketamine then by all means, you do you. If you may be interested in trying ketamine, become a zombie safely, just don't expect it to cure your depression, woes, or any of your other problems.
Yeah, I'm gonna take the peer reviewed studies results that show that ketamine is quite effective with relieving drug resistant depression over this post of yours...
Yeah but I don’t like when peoole see one study and then claim that it’s conclusive. The consensus is that there may there might be something to it being useful for depression, and it should be studied further. No high confidence.
It is useful in creating a sense of disassociation of self - the same thing that meditation does. It even affects the same regions of the brain as meditation. When used carefully, with therapeutic intent, it can be an effective treatment for depression.
Recreational use is sketchy, definitely. But the science is there for using it therapeutically.
I have no dog in this fight, but any studies done on brain chemistry and psychological effects need to be taken with a grain of salt. We know so little about the brain and consciousness that most of the stuff we're trying and doing are educated guesses.
I judge my desire to try drugs by how people act when they’re on them. Do they look like they’re having fun at least? Two drugs I’ve never had an interest in:
That's unfortunate. The effects of many drugs can be entirely mental rather than visual, leaving the person looking like they're just laying down with their eyes closed, or staring into space.
Particularly, ketamine, as a dissociative, at higher doses, is entirely in your mind. What a person in that state looks like from the outside is zero indication of what they are experiencing.
To each their own for sure, but that right there is a combination for some very strange times. Sometimes fun is becoming part of the couch and traveling into outer space. They're definitely not all get up and dance and have fun, though.
I would add to this that anyone doing ketamine should not do it in the bath, which seems to be what happened here. The same happened to someone I knew, she drowned in the tub.
Yeah, "don't k-hole in the bathtub" seems like pretty good (and hopefully obvious) advice. This seems more like user error than the acute effects of the drug itself.
He didn't die from overdosing on ketamine, because that's nearly impossible.
To expand on the urinary issues ketamine causes, the problem is that ketamine will recrystallize inside your blatter and ketamine crystals can be pretty sharp.
MDMA not worth it? It's euphoria and love in a pill, not addictive, and quite safe when you do not abuse it. Millions of people use it and have been using it for about half a century and the vast majority of it restricts it to when they're partying with few side effects. I think you misjudge its use a bit.
Yes it can be acutely abused because you're chasing the dragon on nights that you do use it, but that is also a result of its illegal nature and a lack of education.
Of the chemical variants of drugs, I'd say it's probably one of the few that is actually worth it, besides LSD.
You'd be shocked by how many very successful and incredibly intelligent people have used drugs (including MDMA). Many still use them regularly. MDMA, in the right setting and in moderation, can (will) be a life-affirming and beautiful experience.
This honestly sounds like something a child would say after having D.A.R.E. in elementary school.
Hmmm, I don't know the second one but mdma is great fun. Of course you have to be in a good state of mind before trying, but it's a potent empathogen that has its uses.
It’s how Elijah McClain died too. Young kid stopped by police for matching the description. They shot him full of ketamine and he died of respiratory failure.
Can't recall all the details, but the impression I got was his respiratory failure was caused by the officer choking him with a knee on his windpipe. EMTs did give a very high dose of ketamine at 5mg/kg body weight, whereas I usually use 0.5-1mg/kg body weight to put patients under surgical anesthesia.
I was looking up psilocybin and was surprised to see the mean fatal dose for a bunch of lab animals. Didn't bother equating it to humans, but I was surprised.
it is actually really hard for ketamine to kill you, that is why it was used as anaesthetic in combat medicine, because it is safe to be administered by untrained staff. but it is really important not to anaesthetize yourself in the pool :(.
If another comment was to be believed, he had heart disease. Ketamine plus a hot tub, probably alcohol (? Someone correct me if I'm wrong please) my chest hurts just from thinking about that. His heart probably damn near ruptured
Anything that has the effect of Ketamine would easily kill in the right amount, let alone in a pool of water. If they use it as animal anesthesia its probably pretty potent. Can be fun in the right amounts but got to be safe and careful.
Perry had been undergoing ketamine infusion therapy prior to his death, reportedly for depression and anxiety. The toxicology report adds: “At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression.”
He was getting it as treatment, but technically yes
He was definately taking it recreationally too, a therapeudic dose wouldn't even be close to enough to OD on. Long term ketamine use can have it's own risks if the dose isn't kept very low.
I had no idea about what ketamine actually is, It seemms most likely to me that it was administered via IV by a MD, no? Wasn't this manslaughter by the doctor, then?
If only there were some world-wide interconnected network of computers full of more information than you could possibly imagine, all of it searchable instantly where you could find out who Matthew Perry was.
I remember the world pre-pocket (or home) internet. We thought access to information was the core issue of people being ignorant/misinformed/stupid, surely instant access to world libraries with all the cumulated human knowledge would alleviate that.
Disregarding all the other stuff, the reports say he was being treated with ketamine for anxiety and depression. He had decades of mental health struggles.
No matter who the person is, he was still a person.
From wikipedia: "On December 15, 2023, Perry's death was revealed to have occurred due to "acute effects of ketamine".[94][95] Other circumstances that contributed to his death included the effects of buprenorphine, drowning, and coronary artery disease.[94]" https://en.wikipedia.org/wiki/Matthew_Perry#Death
I was all, "who's Matthew Perry"?