Chernobyl's mutant wolves appear to have developed resistance to cancer, study finds
Chernobyl's mutant wolves appear to have developed resistance to cancer, study finds
The wolves are exposed to cancer-causing radiation as they roam the wastelands of the abandoned city - with researchers finding part of their genetic information seems resilient to increased risk of the disease.
The wolves are exposed to cancer-causing radiation as they roam the wastelands of the abandoned city - with researchers finding part of their genetic information seems resilient to increased risk of the disease.
The researchers discovered that Chernobyl wolves are exposed to upwards of 11.28 millirem of radiation every day for their entire lives - which is more than six times the legal safety limit for a human.
Ms Love found the wolves have altered immune systems similar to cancer patients undergoing radiation treatment, but more significantly she also identified specific parts of the animals' genetic information that seemed resilient to increased cancer risk.
So, is it that they have adapted to the radiation, or that they’re more resistant to cancer? What is the biological and or medical differentiation between these two things, because the article doesn’t really explain that.
I mean, I understand if the answer is, “yes,” but there must be a more meaningful different different differentiation between these two processes. I know I’m asking as a lay person, but is there anyone here who can explain this a little more clearly for the rest of us?
Found an npr interview with the researchers that provides more insight: Why wolves are thriving in this radioactive zone
CAMPBELL-STATON: So in general, we found that the fastest-evolving regions within Chernobyl are in and around genes that we know have some role in cancer immune response or the anti-tumor immune response in mammals.
...
CAMPBELL-STATON: The major question that we had was, is there selection happening? Our data clearly show that there is a genetic component - you know? - and a significant and strong genetic component. That does not mean that the entire story is based around genetics.
BARBER: This might be why the wolf population is thriving. After generations of developing a resilience or resistance to cancer, they're now successful apex predators in an area once devoid of much other life. But Shane says, even if natural selection is at play here, there's another big factor at play.
CAMPBELL-STATON: The other thing is humans aren't there, right? A wolf within the Chernobyl Exclusion Zone - it may have to deal with pressures from cancer, but it doesn't have to deal with pressures from, say, hunting. And it may be that the release from that hunting pressure - that separation from humans - turns out to be a much better thing than having to deal with cancer, which is kind of messed up.
BARBER: So when you think about that initial conundrum - why is the wolf population in Chernobyl estimated to be seven times denser than in other areas? - it's hard to know exactly why. Maybe wolves with cancer-resistant or -resilient genes are naturally selected. Maybe they just don't need to worry about humans. Cara and Shane say it's probably a bit of both, but they hope to take more trips to the CEZ to figure this out. And they also think that if they're able to identify the genes responsible for this cancer resilience or resistance in wolves, it could inform human cancer treatments.
Who knew the Children of Atom would be right?
They weren’t. The radroaches and ghouls, on the other hand…
on the other hand
I see what you did there.
Who knew that wolves in Chernobyl would develop the cure for cancer?
What a crazy thing to happen!
So... Are you suggesting that the cure to cancer is to be born as a wolf in Chernobyl?
Thanks, I'm cured!
In Ukraine, so Mutant War Wolves
There are mRNA treatments in test that have near 100% effectiveness in mice.
I imagine there are a whole mess of asterisks on this factoid.