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DelightfullyDivisive @lemmy.world
Posts 16
Comments 37
Microsoft blocks Windows 11 workaround that enabled local accounts
  • A couple of people mentioned Linux. I switched my main laptop to it 2 months ago. (Mint, specifically.)

    I use it for work (office apps, chat apps like slack and teams, XMind, Joplin, TickTick), to play BG3, and some light programming in Python. It has been my daily driver at a new job (SE director), and I never use the Macbook they sent me.

  • Detroit just had it's first population growth in 66 years. Huzzah!
  • Yes. I've been told that by cops in prior years.

    That said, things have improved enormously in the last 10 years. There is a vibrant downtown area, and fairly large pockets of redevelopment around it, with safe(-ish) and affordable housing.

  • Detroit just had it's first population growth in 66 years. Huzzah!
  • I think most Americans like the idea of public transport, and including a robust national rail network. The reason it doesn't exist are the oil and automotive lobbies. (Mostly oil.). Poorly educated Americans (the ones wearing MAGA hats) are easy to manipulate by these groups, as well.

  • My first grade report card from 1982
  • I was diagnosed at the age of 56. It might be worth you trying meds again. I have found Strattera to be extremely helpful to me.

    And I followed every productivity guru in the world for decades just to try to keep things going for myself professionally. I have so internalized that I am just lazy and need to rail on myself to keep myself in line, that even though I know it isn't true I still do it to some extent.

  • Doctor recommended trying Strattera, looking for other users experiences
  • I don't notice anything else related to vasoconstriction. My BP hasn't changed since I started on it, for instance. It doesn't really affect my appetite for sex, just my ability. This has lessened over time, but it's still present. (And after ~8h, everything is fine.)

    You can take it before bed if you like. Some people find it sleep-inducing at first. I find it simulating an hour or two later.

    From what I have read, there are several different experiences from it. You'll likely have to try it and see how it works for you, and what accommodations you'll need to make. Hopefully the comments in this thread give you an idea of what to look out for.

  • Doctor recommended trying Strattera, looking for other users experiences
  • Yes, its daily. It took a few days to notice a difference for me, but it definitely helps me with executive function. I'm up to the max dosage after 18 months, but it's still working.

    Side effects for me are nausea for maybe an hour after I take it, and major "shrinkage". Sex is a real challenge for around 8h after taking it, and it looks like I've been swimming in the Arctic sea for about that long. This isn't a major problem because I take it in the morning, but it has been occasionally frustrating. That effect wears off by evening, though, so my spouse is ok with me taking it. 🙂

    I have never taken stimulants, so I can't offer a comparison there.

  • A realistic take on rescheduling

    It's a step forward, but there is still a long way to go for full legalization.

    1
    DJI might get banned next in the US
  • Is there a good source explaining how these drones are used in the US by the Chinese govt? Are they sold to consumers, but upload to a China-based cloud? There was zero background in that article.

  • U.S. bans noncompete agreements for nearly all jobs
  • I have been told (by my attorney) that arbitration is sometimes more expensive than filing suit. IIRC, the rationale is that arbitration can have very high fees and involve a large number of people. It was in the context of drawing up a boilerplate nda, but it has been awhile and I don't remember the details.

  • Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    As more people are eating healthier diets, CNBC worries that it will cut into the profits of purveyors of unhealthy foods

    www.cnbc.com Most people on weight loss drugs are spending less on restaurants and takeout, survey says

    The findings add to concerns that GLP-1s could take a bite out of the bottom lines of some of the biggest restaurant companies and packaged food makers.

    Most people on weight loss drugs are spending less on restaurants and takeout, survey says

    Given the popularity of these medications, it's still amazing to me that we don't see more articles about how it has changed the lives of many people. Nor have I seen much about how traumatic the shortages can be to people who have longed for positive results in their weight loss journey for years, only to have that hope taken away by an inability to obtain their medication.

    8
    What are you using AI (ChatGPT, Perplexity AI) for in your daily routine?
  • I've tried paid versions of ChatGPT, Claude, and Gemini. I am currently using Gemini, and it is working reasonably well for me.

    I mostly use it to replace searches. I haven't used Google in years, but mainly relied on DuckDuckGo until SEO made it less useful. My secondary use case is for programming. I tend to jump around to a lot of different languages and frameworks, and it's hugely helpful to get sample code describing what I want to do when I don't know the syntax.

    Once in a great while, I will have it rewrite something for me. That is mostly for inspiration if I want to change the tone of something I wrote (then I'll edit). I think that all of the LLMs suck at writing.

  • Trump’s Bizarre Rants Over Wind Power Are More Ominous Than You Think
  • I would love to understand this better. I have worked in power generation before (writing maintenance software for a nuclear plant, so I picked up a few things). I don't understand the distribution side at all, though.

    Can you suggest a book or article on the subject?

  • Trump’s Bizarre Rants Over Wind Power Are More Ominous Than You Think
  • Renewables are an important part of the mix, but seems like nuclear is more important right now. It's the best way to move industry away from coal and gas in the long run, though it's something we in the US should have started on 30 years ago.

    I'm aware that nuclear power has it's own set of complications, but they're more solvable than reducing emissions without it

  • Someone silently made an open source GPU!
  • Non-competes aren't enforceable, but proprietary "work-for-hire" clauses might be. I think the difference is that a company can't stop you from working for a competitor, but they can force you to sign away your rights to anything you create while employed there. I have worked for a couple of big-box consulting companies, and they have you list anything you created before joining them, so any new creations are automatically theirs.

  • A community for people using GLP-1 medications for weight loss

    lemmy.world Zepbound, Weygovy, Mounjaro and other GLP-1 medications - Lemmy.World

    Discussions about weight loss, challenges and victories (on the scale and otherwise) using GLP-1 medications.

    Check out Zepbound at lemmy.world.

    This is a community for anyone who is using or plans to use Ozempic, Zepbound or any of the other peptide-based obesity/diabetes drugs. Share information, hacks and get support!

    0
    Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    Shortage problems?

    Has anyone had luck in getting their medication recently? My local pharmacy substituted a box of Mounjaro for me. (It's also tirzepatide, just marketed for diabetes instead of obesity.)

    0

    A cosmology without dark matter

    I haven't found anything calling this crank science, although it does make some rather sweeping claims. One is that dark matter does not exist, and another is that the universe is 27 billion years old.

    https://phys.org/news/2024-03-universe-dark.html

    13

    Crisis in cosmology? Or just tweaking models?

    I have read several articles like this one.

    https://www.livescience.com/space/cosmology/james-webb-telescope-confirms-there-is-something-seriously-wrong-with-our-understanding-of-the-universe

    They all seem to be saying that there is a "crisis in cosmology", where different measurements can't reconcile what the value of the hubble constant is.

    Then I watched this video last night that seems to be saying it's all just tweaking different models.

    https://youtu.be/2pux7v9qJ58?si=ux3zBSHR-vvsz9qY

    I'm not entirely sure if they're talking about two slightly different things. (Hubble's constant, and the predicted age of the universe.) Or if the "crisis" is really just a misunderstanding, or just clickbait tactics. Any informed opinions on the subject?

    5

    A newly-discovered volcano on Mars

    scitechdaily.com Mars Unmasked: Giant Volcano and Hidden Ice Challenge Old Theories

    A deeply eroded giant volcano, active from ancient through recent times and with possible remnants of glacier ice near its base, had been hiding near Mars’ equator in plain sight. Its discovery points to an exciting new place to search for life, and a potential destination for future robotic and hum

    Mars Unmasked: Giant Volcano and Hidden Ice Challenge Old Theories
    3
    Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    Some useful information

    This seemed quite informative & a way to kick off some conversation, so I’m crossposting from Reddit’s /r/zepbound sub.

    I have worked on this over time in the Mounjaro sub but thought I would post it as it might help a few people.

    These are not set rules, but rather a guide that has been found helpful by myself and others. In the early stages of taking the drug, the following steps may prove to be helpful: Taking the Medicine

    Wait several weeks after picking up the prescription prior to starting. This will give you buffer for supply shortages in the future. These are very real and very impactful so while not required this is highly recommended. Go buy the OTC meds listed below in the side effects. These are for just in case they are needed. Store your pens in the box and keep inside your refrigerator. Remember vibration, light, extreme cold or heat above 80 degrees Fahrenheit will reduce the effectiveness of your drug. Read the booklet inside the box before you do anything. Seriously read it! Be intentional about selecting your shot day. For example, doing it on a Friday means experiencing maximum effect over the weekend when tendency to indulge is typically high Re: selecting injection day. Or, you may wish to inject on a Wednesday or Thursday if you experience side effects for a day or two after injection. (so, by the weekend, you’re feeling great and hunger suppression is still strong enough to counter any temptation to over-indulge) Make a choice that works for your life. If you need to move your shot day you may do so as long as you don’t take two doses in under 4 days or more than 14 days apart. Under 4 may result in too much medicine in your system. Over 14 days and Eli Lilly recommends starting over from 2.5mg. Either way consult your doctor prior for either scenario. Select an injection site location and be sure to rotate between several locations. The injection is hardly noticeable but if you let the pen come to room temp for 30 minutes prior to the shot you will not get a burning sensation from the cold. If the pen malfunctions or you have any issues / questions post injection then call Eli Lilly ASAP. Number on the box! KEEP THE PEN. Don’t discard as Eli Lilly may offer to exchange the pen. Process a refill as soon as you use pen #3 in each box. Note: If you have a prescription that allows for a 3 month supply then get all 3 months. This will help you manage through potential shortages.

    Lifestyle Changes

    Drinking 32oz of water three times a day helps regulate digestion. Incorporating lean meats and green vegetables in meals provided essential nutrients and fiber while protein helps alleviate tiredness, and vegetables regulated constipation. It’s advisable to minimize fat, sugar, and carbs during this period for better results. Purge your house of highly processed or sugary foods, and avoid artificial sweeteners as they interfere with the medicine’s glucagon impact. Pick a weigh-in day and maintain regularity. Don’t be surprised or discouraged by stalls that occasionally last weeks or even a month as they are normal. Aim for slow, healthy weight loss of around 2 pounds per week. Track calories and macros using an app of your choice. Use this journey to change the way you eat, learn about your nutritional needs, and focus on eating healthier, decreasing the loss of lean muscle mass. Get into a fitness routine or some sort. This does not have to be drastic are rigorous but again success with Mounjaro is about changing your lifestyle and health trajectory of which weight loss is just one key metric.

    As Your Journey Progresses

    Be ready to titrate up but not too eagerly. One does not have to get to 15mg unless their doctor advises otherwise. Work with your doctor to find the correct dosage, and avoid rushing to the top. This also helps keep weight loss in the 2lb range, preventing loose skin, hair loss, and other side effects of rapid weight loss. Start planning for what life looks like at the end of the weight loss journey. This process is called maintenance, and it is vital to keep sight of what happens afterward. It’s essential to avoid being a statistic and gaining back 80% of the lost weight. Regularly test your fasting Glucose, A1C, blood pressure, heart rate and cholesterol panel. This may be needed in the future to support insurance claims or future PAs.

    Managing Side Effects:

    Taking Pepto as needed may help reduce (sulfur) burps. This may turn you tongue black which is normal. Taking a Pepcid Complete as needed may help alleviate heartburn. Taking Imodium as need for for diarrhea. Taking stool softeners as needed aids with constipation early.

    Note: Some people have no side effects and some people have a lot. Each person is different. If you don’t have indigestion, don’t the med but have it on hand. Some people have diarrhea instead of constipation, so be prepared but see if you have a side effect before assuming you will have it and taking another medication. Don’t be afraid of side effects or giving shots or any of the other fear thoughts that are stopping you from opening that box and changing your life. You got this!

    0
    Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    A podcast with some useful information

    From a doctor in an online obesity clinic. They have a lot of clinical experience with semaglutide and tirzepitide. This is a link to their online practice. (Note that I am not a member or affiliated in any way.)

    For the podcast, you can search "Beyond the Scale with Dr. Spencer Nodolsky" in your favorite app, and it's available on YouTube as well.

    I have listened to several episodes, and keep coming across interesting tidbits from their clinical practice. It isn't entirely focused on GLP-1 medication, but you can pull out the ones with "GLP-1" in the title. It looks like they have been on a break since November, but they were using all of the current GLP-1s in their practice as of last Oct-Nov.

    A few perspectives I have picked up from listening:

    • It is important to eat enough on these meds. It's healthier (from a psychological change-your-relationship-to-food perspective and from a physical health perspective) to get good nutrition and lose weight at a sustainable pace of <= 1.5% body weight per week. Use the med to help you eat smaller portions and avoid snacking, not to avoid eating all day.
    • "Food Noise" reduction is a thing for most people they've seen. Although none of the meds were on-label for binge eating disorder, they have found that GLP-1's are an excellent treatment for that, and they tied it to "food noise".
    • Most of the advice I've seen in this subreddit for side-effects is covered, and they offer some additional details, so worth a listen.
    • They have seen both ends of the bell curve with hypo-and-hyper-responders to the meds. They usually try a different med to resolve that, but insurance can be a hassle in that case. Worth a listen if you are seeing good results with 2.5mg, or if you're titrating up & results are still suboptimal.

    I have only listened to a handful of episodes, but they have all had useful information. If you listen to podcasts (I like them while doing housework or working out), I recommend this one.

    0
    Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    Increase in DOMS?

    Another of my posts from Reddit in recent weeks:

    Does anyone else experience an increase in DOMS (delayed-onset muscle soreness) after starting zepbound? I have ramped up the intensity of my workouts lately, and it seems like muscle soreness has gotten much worse.

    I'm thinking I should dial it back a bit, because it is also stimulating quite a bit of appetite. Not really what I want when I'm trying to cut calories and weight. 🤔

    Addendum: The consensus was that a lot of people experienced more difficulty completing endurance workouts, but not specifically weight training (which is where DOMS usually comes from).

    1
    Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    This article discusses one of the most profound realizations I have had from using Zepbound

    www.businessinsider.com Weight wasn't the only thing I lost when I took a weight-loss drug

    I knew weight-loss drugs would change my body. I wasn't prepared for what they would do to my brain.

    Weight wasn't the only thing I lost when I took a weight-loss drug

    ...and here is what I posted on Reddit in January on this subject:

    I feel less of a sense of shame about my eating habits now

    For most of my adult life, I have held a core belief that I am just "weak-willed". My weight and eating habits were at the core of this belief. After all, eating is an intentional act - an effort of will. If you eat sugary carbohydrates, or just very large portions of anything when you're already overweight, it's just a failure of willpower, right?

    Zepbound is changing that for me. The effect was immediate and dramatic in my first week using it. I wasn't hungry and felt full quickly, as expected. The surprise was that I didn't even think about food. I understood immediately what people meant by "food noise" abating when on a GLP-1 medication.

    And that's what is causing this sense of shame to abate. If a drug can eliminate thought patterns that I have engaged in for 30 years, do those thoughts really have anything to do with willpower? I think not. I see those thoughts now as being purely physiological at their source, and people who don't (or rarely) have food cravings aren't stronger willed than I am, they were just fortunate in the genetic lottery.

    It's a good feeling to drop that shame. Or it will be, when I can finally let most of it go. I have consciously and unconsciously carried this feeling around for decades. I'm still carrying some around now, even though the rational part of my mind is already convinced.

    If you have felt ashamed of being overweight (and I expect that nearly all of us have), consdier what I'm saying, and see if you can cut yourself some slack.

    0
    Zepbound, Weygovy, Mounjaro and other GLP-1 medications @lemmy.world DelightfullyDivisive @lemmy.world

    Welcome!

    I checked the other communities in this space, and they're completely inactive and (apparently) unmoderated. Since I'm a few months into this journey, and I love to really dig in to topics, I decided to create a community & see if others are interested in it.

    0

    You got a box of Zepbound - now what?

    This seemed quite informative & a way to kick off some conversation, so I'm crossposting from Reddit's /r/zepbound sub.

    I have worked on this over time in the Mounjaro sub but thought I would post it as it might help a few people.

    These are not set rules, but rather a guide that has been found helpful by myself and others. In the early stages of taking the drug, the following steps may prove to be helpful:

    Taking the Medicine

    • Wait several weeks after picking up the prescription prior to starting. This will give you buffer for supply shortages in the future. These are very real and very impactful so while not required this is highly recommended.
    • Go buy the OTC meds listed below in the side effects. These are for just in case they are needed.
    • Store your pens in the box and keep inside your refrigerator. Remember vibration, light, extreme cold or heat above 80 degrees Fahrenheit will reduce the effectiveness of your drug.
    • Read the booklet inside the box before you do anything. Seriously read it!
    • Be intentional about selecting your shot day. For example, doing it on a Friday means experiencing maximum effect over the weekend when tendency to indulge is typically high Re: selecting injection day. Or, you may wish to inject on a Wednesday or Thursday if you experience side effects for a day or two after injection. (so, by the weekend, you’re feeling great and hunger suppression is still strong enough to counter any temptation to over-indulge) Make a choice that works for your life.
    • If you need to move your shot day you may do so as long as you don’t take two doses in under 4 days or more than 14 days apart. Under 4 may result in too much medicine in your system. Over 14 days and Eli Lilly recommends starting over from 2.5mg. Either way consult your doctor prior for either scenario.
    • Select an injection site location and be sure to rotate between several locations. The injection is hardly noticeable but if you let the pen come to room temp for 30 minutes prior to the shot you will not get a burning sensation from the cold.
    • If the pen malfunctions or you have any issues / questions post injection then call Eli Lilly ASAP. Number on the box! KEEP THE PEN. Don’t discard as Eli Lilly may offer to exchange the pen.
    • Process a refill as soon as you use pen #3 in each box. Note: If you have a prescription that allows for a 3 month supply then get all 3 months. This will help you manage through potential shortages.

    Lifestyle Changes

    • Drinking 32oz of water three times a day helps regulate digestion.
    • Incorporating lean meats and green vegetables in meals provided essential nutrients and fiber while protein helps alleviate tiredness, and vegetables regulated constipation.
    • It’s advisable to minimize fat, sugar, and carbs during this period for better results.
    • Purge your house of highly processed or sugary foods, and avoid artificial sweeteners as they interfere with the medicine’s glucagon impact.
    • Pick a weigh-in day and maintain regularity. Don’t be surprised or discouraged by stalls that occasionally last weeks or even a month as they are normal. Aim for slow, healthy weight loss of around 2 pounds per week.
    • Track calories and macros using an app of your choice. Use this journey to change the way you eat, learn about your nutritional needs, and focus on eating healthier, decreasing the loss of lean muscle mass.
    • Get into a fitness routine or some sort. This does not have to be drastic are rigorous but again success with Mounjaro is about changing your lifestyle and health trajectory of which weight loss is just one key metric.

    As Your Journey Progresses

    • Be ready to titrate up but not too eagerly. One does not have to get to 15mg unless their doctor advises otherwise. Work with your doctor to find the correct dosage, and avoid rushing to the top. This also helps keep weight loss in the 2lb range, preventing loose skin, hair loss, and other side effects of rapid weight loss.
    • Start planning for what life looks like at the end of the weight loss journey. This process is called maintenance, and it is vital to keep sight of what happens afterward. It’s essential to avoid being a statistic and gaining back 80% of the lost weight.
    • Regularly test your fasting Glucose, A1C, blood pressure, heart rate and cholesterol panel. This may be needed in the future to support insurance claims or future PAs.

    Managing Side Effects:

    • Taking Pepto as needed may help reduce (sulfur) burps. This may turn you tongue black which is normal.
    • Taking a Pepcid Complete as needed may help alleviate heartburn.
    • Taking Imodium as need for for diarrhea.
    • Taking stool softeners as needed aids with constipation early.

    Note: Some people have no side effects and some people have a lot. Each person is different. If you don’t have indigestion, don’t the med but have it on hand. Some people have diarrhea instead of constipation, so be prepared but see if you have a side effect before assuming you will have it and taking another medication. Don’t be afraid of side effects or giving shots or any of the other fear thoughts that are stopping you from opening that box and changing your life. You got this!

    Have additional issues or questions about Mounjaro, please head to:

    Mounjaro Website___

    0