Makes me wonder if it's actually possible to make shaped balloons like that. Maybe with loops of strings embedded in the rubber, to prevent certain parts from inflating more than that diameter. if this is not already a thing, it should be a thing!
You wouldn't be able to make detailed shapes from a round balloon, like in the comic, but if the balloon was already shaped like a horse when deflated, it might be possible
I think with enough R&D into specialized balloon-manufacture techniques, it would be possible to make round balloons that inflate into a different discernable shape. But it wouldn't be as detailed or precise as in the comic.
You could do this very easily if the balloon was made of beach ball material. Of course it might be obvious what the final shape was supposed to be when it was deflated.
According to know your meme he is originally from Facebook. Here is the source image on Instagram but apparently remade later: https://www.instagram.com/p/BqMZi2lAGsr/