Biomolecular condensates mediate bending and scission of endosome membranes | Nature
Biomolecular condensates mediate bending and scission of endosome membranes | Nature
Multivesicular bodies are key endosomal compartments implicated in cellular quality control through their degradation of membrane-bound cargo proteins1–3. The ATP-consuming ESCRT protein machinery mediates the capture and engulfment of membrane-bound cargo proteins through invagination and scission ...
We propose that condensate-mediated scission represents a previously undescribed scission mechanism that depends on the physicomolecular properties of the condensate and is involved in a range of trafficking processes.
I understood some of those words.
"previously undescribed" are the ones getting my attention. That usually indicates major new breakthroughs ahead (assuming others can replicate the findings).
I got "and" and "Nature".
The rest I have to look up.
