Edit: As people in the comments pointed out, this bill targets all websites hosting porn. e621 just happens to be hosted in Arizona, and it therefore affects them directly.
...PUBLISHES OR DISTRIBUTES MATERIAL HARMFUL TO MINORS ON THE INTERNET FROM A WEBSITE THAT CONTAINS A SUBSTANTIAL PORTION OF MATERIAL HARMFUL TO MINORS...
Since furry porn isn't harmful, they should be ok.
How much is a "substantial amount"? There's not thaaat much porn on e621, most of it is marked safe
Well a lot of it is...
Well some of it is...
I'm relatively sure i saw one marked safe once...