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What's your favourite search engine?
  • In my case I've found the need to use Google for local searches, and certain very specific searches (one example is journal impact factors). In a lot of other cases, DDG has actually given me better results - I was getting fed up with some of the crappy results I was getting using Google, which prompted me to try out and eventually shift to DDG.

  • scitechdaily.com Scientists Pinpoint Main Cause of Sensory Hypersensitivity in Autism

    Sensory hypersensitivity in mice with Grin2b mutations is associated with hyperactivity in the anterior cingulate cortex and increased connectivity throughout the brain. A research team led by Director Kim Eunjoon of the Center for Synaptic Brain Dysfunctions and Director Kim Seong-Gi of the Center

    Scientists Pinpoint Main Cause of Sensory Hypersensitivity in Autism

    This study has identified the anterior cingulate cortex (ACC) as a key area in the brain responsible for sensory hypersensitivity in autism spectrum disorders. Utilizing a mouse model with a Grin2b gene mutation, heightened neural activity and connectivity in the ACC was observed. Suppressing this hyperactivity normalized the sensory hypersensitivity, offering new insights into treatment options

    https://www.nature.com/articles/s41380-024-02572-y (open access)

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    Wacky migraine soothing techniques?
  • I've found that applying an ice pack on my forehead and neck helps a little. Not much else by way of wacky treatments. The most effective one is my sumatriptan. It's a life saver for me!

  • Star Trek Technobabble - YouTube
    youtube.com Star Trek Technobabble

    Star Trek technobabble rapWe got a subspace anamoly, a graviton pulsewe got a catastrophic diagnostic cycle resultinertial dampeners just went offlineand tha...

    Star Trek Technobabble

    Really enjoyed this one.

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    www.nature.com Brain-reading device is best yet at decoding ‘internal speech’

    Technology that enables researchers to interpret brain signals could one day allow people to talk using only their thoughts.

    Brain-reading device is best yet at decoding ‘internal speech’

    Brain-machine interfaces implanted in the participants of this study in the supramarginal gyrus (SMG) and primary somatosensory cortex (S1) were successfully able to decode both internally spoken and vocalized words.

    https://www.nature.com/articles/s41562-024-01867-y?utm_source=Live+Audience&utm_campaign=1586f44658-nature-briefing-daily-20240514&utm_medium=email&utm_term=0_b27a691814-1586f44658-52006460 (open access)

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    www.nature.com Human embryos embrace asymmetry to form the body

    The cells generated by the very first division of the fertilized egg make a lopsided contribution to the body’s organs and tissues.

    Human embryos embrace asymmetry to form the body

    This study performed lineage tracing of live human embryos from the first cleavage division until the blastocyst stage and discovered that the majority of cells in the EPI, the future human body, originate from one of the two cells in most embryos. The first blastomere to divide at the 2-cell stage has a higher likelihood to generate the first, and more, internalized cells at the 8-to-16-cell stage.

    https://www.cell.com/cell/fulltext/S0092-8674(24)00455-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867424004550%3Fshowall%3Dtrue (open access)

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    bigthink.com The scientific story behind the timeline of our Universe

    From the earliest stages of the hot Big Bang (and even before) to our dark energy-dominated present, how and when did the Universe grow up?

    The scientific story behind the timeline of our Universe

    An interesting article on the time line of the universe.

    The Universe passed through many epochs, from free quarks and gluons to stable protons and neutrons to neutral atoms to stars, galaxies, planets, and more. The precise time at which these various epochs occurred, including the (current) dark energy-dominated era, can be pinpointed with precision. Here’s how we know.

    5
    scitechdaily.com New Study Links Complex Jobs to Reduced Risk of Dementia

    A recent study from Columbia University Mailman School of Public Health, the Columbia Aging Center, and the Norwegian Institute of Public Health found that individuals who engaged in mentally stimulating jobs during their 30s to 60s were less likely to develop mild cognitive impairment (MCI) and dem

    New Study Links Complex Jobs to Reduced Risk of Dementia

    A cohort study found that individuals who engaged in mentally stimulating jobs during their 30s to 60s were less likely to develop mild cognitive impairment (MCI) and dementia after turning 70, highlighting the importance of cognitive stimulation during midlife for maintaining cognitive function in old age. [It is important to note that this study identifies associations rather than direct causation of dementia.]

    https://www.neurology.org/doi/10.1212/WNL.0000000000209353

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    That time when Microsoft bought and killed Nokia phone unit
  • I've been enjoying the launcher 10 launcher on my phone for more than two years now. Whenever I change my launcher, I keep going back to it. I find it to be so productive for my use. And the windows 10 live tiles ui is also great.

  • scitechdaily.com Engineering Life: Chemists Have Created the Functional Synthetic Cells That Act Like Real Ones

    Researchers employ cutting-edge methods to create functional cells, closing the divide between synthetic and biological materials. In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins —

    Engineering Life: Chemists Have Created the Functional Synthetic Cells That Act Like Real Ones

    The engineering of artificial cells requires a reconfigurable cytoskeleton that can organize at distinct locations and dynamically modulate its structural and mechanical properties. This study combines peptide self-assembly with DNA programmability to realize a synthetic cytoskeleton in droplets showing that programmable peptide–DNA nanotechnology approach is a powerful platform towards the construction of functional, fully artificial cells.

    https://www.nature.com/articles/s41557-024-01509-w (open access)

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    Paedophiles create nude AI images of children to extort from them, says charity | Internet safety | The Guardian
    www.theguardian.com Paedophiles create nude AI images of children to extort from them, says charity

    Internet Watch Foundation has found a manual on dark web encouraging criminals to use software tools that remove clothing

    Paedophiles create nude AI images of children to extort from them, says charity

    Internet Watch Foundation has found a manual on dark web encouraging criminals to use software tools that remove clothing. The manipulated image could then be used against the child to blackmail them into sending more graphic content, the IWF said.

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    TechScape: No WhatsApp in China, no TikTok in the US, and the return of Llama | Technology | The Guardian
    www.theguardian.com TechScape: No WhatsApp in China, no TikTok in the US, and the return of Llama

    In this week’s newsletter: While Apple removed the platform from App Stores without a squeak of public protest, its battle with the EU rages on. Plus, how a ban in the US could change TikTok everywhere

    TechScape: No WhatsApp in China, no TikTok in the US, and the return of Llama

    While Apple removed the platform from App Stores without a squeak of public protest, its battle with the EU rages on.

    "When an authoritarian regime tells Apple what it can do with the App Store, the company’s response is a curt single paragraph. When a democratic union tries to do the same, the response is vociferous and negative."

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    www.theguardian.com The new science of death: ‘There’s something happening in the brain that makes no sense’

    The long read: New research into the dying brain suggests the line between life and death may be less distinct than previously thought

    The new science of death: ‘There’s something happening in the brain that makes no sense’

    "For all that science has learned about the workings of life, death remains among the most intractable of mysteries....

    "New research into the dying brain suggests the line between life and death may be less distinct than previously thought...

    "Death may be far more alive than we ever thought possible..."

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    scitechdaily.com Decoding the Origin of Life: Scientists Solve Early Earth RNA Puzzle

    Recent research illustrates how RNA molecules' chemical characteristics might have played a crucial role in the development of complex life forms. How did complex life manage to evolve on the early, inhospitable Earth? Initially, ribonucleic acid (RNA) must have existed to carry the first genetic i

    Decoding the Origin of Life: Scientists Solve Early Earth RNA Puzzle

    This study reveals how life’s complexity could originate from simple RNA molecules on early Earth. Through experiments demonstrating RNA’s recycling and replication abilities under conditions such as low salinity and high pH, the research suggests life could emerge from minimal molecular sets in environments akin to volcanic islands. This means that an RNA world could arise without the prior necessity for long complex sequences.

    https://pubs.acs.org/doi/10.1021/jacs.3c10813# (open access)

    0
    bigthink.com What was it like when planet Earth first formed?

    The Earth that exists today wasn't formed simultaneously with the Sun and the other planets. In some ways, we're quite a latecomer.

    What was it like when planet Earth first formed?

    An article which explains the formation of Earth and our solar system.

    0
    scitechdaily.com New Research Reveals Keto Diet’s Potential To Combat Early Alzheimer’s

    A molecule found in the diet could play a significant role in slowing the progression of Alzheimer's disease. A recent study conducted by scientists at the University of California, Davis, reveals that a ketogenic diet can significantly delay the early stages of Alzheimer’s-related memory loss in m

    New Research Reveals Keto Diet’s Potential To Combat Early Alzheimer’s

    This study shows that a ketogenic diet slows early Alzheimer’s memory loss in mice, in which the molecule beta-hydroxybutyrate (BHB), plays an important role thus offering hope for its application in human ageing and cognitive health.

    https://www.nature.com/articles/s42003-024-05860-z (open access).

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    scitechdaily.com Genetic Relics: How Ancient Viral DNA Could Accelerate Neurodegeneration

    Researchers See Ancient Genes As Potential Targets for Dementia Treatment Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers at DZNE come to this conclusion on the basis of studies on cell cultures. They

    Genetic Relics: How Ancient Viral DNA Could Accelerate Neurodegeneration

    This study uncovers that activation of endogenous retroviruses affects prion-like spreading of proteopathic seeds. It supports that endogenous retroviruses play a role in protein misfolding diseases and suggest that antiviral drugs could represent promising candidates for inhibiting protein aggregate spreading.

    https://www.nature.com/articles/s41467-023-40632-z (open access)

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    scitechdaily.com Scientists Discover “Molecular Rosetta Stone” – Findings Reveal How Our Microbiome Talks to Us

    Scientists at the Skaggs School of Pharmacy and Pharmaceutical Sciences, part of the University of California San Diego, have discovered thousands of new bile acids. These molecules are used by our gut microbiome to communicate with the rest of the body. “Bile acids are a key component of the lan

    Scientists Discover “Molecular Rosetta Stone” – Findings Reveal How Our Microbiome Talks to Us

    This study has used publicly available MS/MS spectra for bile-acid-selective ion patterns to identify thousands of polyamine bile amidates. It highlights the existence of many more bile acid modifications than previously recognized and the value of leveraging public large-scale untargeted metabolomics data to discover metabolites.

    https://www.cell.com/cell/fulltext/S0092-8674(24)00185-5?\_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867424001855%3Fshowall%3Dtrue (open access)

    2
    The Secret behind Metformin’s weightloss-effect
    scitechdaily.com Metformin’s Secret Unleashed: The Anti-Hunger Molecule Mirroring Exercise

    A Stanford Medicine study found that metformin, a commonly prescribed diabetes drug associated with moderate weight loss, stimulates production of lac-phe, a molecule abundant after exercise. An “anti-hunger” molecule produced after vigorous exercise is responsible for the moderate weight loss caus

    Metformin’s Secret Unleashed: The Anti-Hunger Molecule Mirroring Exercise

    Metformin is a widely prescribed anti-diabetic medicine that also reduces body weight. There is ongoing debate about the mechanisms that mediate metformin’s effects on energy balance. This study shows that metformin induces the formation of hunger-reducing metabolite N-lactoyl-phenylalanine (Lac-Phe), a byproduct of muscle fatigue and an amino acid called phenylalanine, found after heavy exercise.

    https://www.nature.com/articles/s42255-024-00999-9

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    scitechdaily.com Worrying – Breast Cancer Rates Are Increasing Among Younger Women

    Examining rates based on age, race, and tumor characteristics could guide the development of prevention strategies. Over the past twenty years, there has been a consistent rise in breast cancer diagnoses among women younger than 50, with the rate of increase becoming more pronounced in recent years

    Worrying – Breast Cancer Rates Are Increasing Among Younger Women

    Breast cancer diagnoses in women under 50 have increased significantly in the past two decades, primarily driven by estrogen-receptor positive tumors. This research highlights the importance of early detection and the need for prevention strategies. Prevention efforts in young women need to adopt a targeted approach to address racial disparities in incidence rates observed at different age phases.

    https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2814306 (open access)

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    Efforts taken by Ancient Rome to fight against voter intimidation − a political story told on a coin that resonates today
    theconversation.com Ancient Rome successfully fought against voter intimidation − a political story told on a coin that resonates today

    Fighting for voter access is an inevitable part of any democracy, from ancient Rome to the US today. Roman legislators were able to thwart elite political sway by introducing written ballots.

    Ancient Rome successfully fought against voter intimidation − a political story told on a coin that resonates today

    An interesting story of how a silver denarius, minted over 2,000 years ago, reveals efforts taken by Ancient Rome to counter voter intimidation and manipulation during elections.

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    scitechdaily.com Scientists Shatter Records With Revolutionary 27.1% Efficient Triple Junction Solar Cell

    Researchers at the National University of Singapore (NUS) have developed a novel triple-junction perovskite/Si tandem solar cell that can achieve a certified world-record power conversion efficiency of 27.1 percent across a solar energy absorption area of 1 sq cm. This achievement marks the highest

    Scientists Shatter Records With Revolutionary 27.1% Efficient Triple Junction Solar Cell

    This study demonstrates, for the first time, the successful integration of cyanate into a perovskite solar cell to develop a cutting-edge triple-junction perovskite/Si tandem solar cell,proving cyanates to be viable substitute for halides in perovskite-based solar cells. An efficiency of 27.1 percent was achieved.

    https://www.nature.com/articles/s41586-024-07226-1

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    InitialsDiceBearhttps://github.com/dicebear/dicebearhttps://creativecommons.org/publicdomain/zero/1.0/„Initials” (https://github.com/dicebear/dicebear) by „DiceBear”, licensed under „CC0 1.0” (https://creativecommons.org/publicdomain/zero/1.0/)BE
    Bebo @literature.cafe
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