The ultimate GTA. All of the best engines in one game. Driving physics from Assetto Corsa/Gran Turismo. Soft-body physics from BeamNG. Flying from Flight Simulator/DCS. VR mode a la Alyx. Shooting from RDR2, melee from Sekiro or similar. When you stop to play basketball, it's proper basketball a la 2K or Live. Same for pool, bowling, etc. Destructible environments like Battlefield or Teardown. Choices matter. Written by the guys who did Disco Elysium and the guys who did Portal/Portal 2.
For me, it would be a new entry in the Legacy of Kain series. I really like "Blood Omen: Legacy of Kain" (first entry) and since Crystal Dynamics launched a poll asking what players liked in the previous games and would like to see in the future, I really hope they publish a new entry one day. Personally, I would prefer a remake of the Soul Reaver trilogy, because with the latest technology it would be a blast.
I used DuckStation to play the first game. It's really well made, the voice acting and presentation are great, and thanks to cheats, I didn't get stuck in annoying areas. The MandaloreGaming channel has a very good review of it.
Blood Omen 2 though... It's a game. It's not terrible, but it feels detached from the rest of the series and has questionable writing. This one can be skipped in my opinion.
I loved the Shining Force games and I would have loved to see Camelot stay with the series and continue it with SF4+ instead of just making the Mario sports games like they do now.
A Superman game that's like Spider-Man PS4. Where you can fly around, explore Metropolis and complete sidequests and that has some levels where you play Lois -- Only unlike MJ, she actually gets to punch someone and fight her way out of it if she's caught sneaking around.