Not counting music, I assume - I have a gazilion artists I love if anyone's interested.
As for actual Content with a capital C:
PhilosophyTube
Extremely interesting, well-researched and entertaining presentation of a wide range of philosophical and sociopolitical topics. From the UK.
Shaun Ditto, though with a different angle and a Northern accent.
Contrapoints Ditto, but American and quite a bit more... theatrical. Quite a strong focus on gender and transgender issues; check out her video on J. K. Rowling for one of the best treatments of the topic.
Dr. Geoff Lindsey - Linguistics and phonology stuff, deep dives into pronunciation, fascinating as fuck.
Middle Eats Really damn good middle-eastern cooking channel, no-nonsense presentation.
Brian Lagerstrom - Baking / cooking - good recipes, sensible treatment.
Tom Scott has finished up his Things You Might Not Know series, but there's like a decade of them and they're amazing. Little investigative videos on everything from programming to wasp farming. You need to watch all of them.
Taylor Tries Videos on juggling. I have the hugest talent-crush.