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TIL psychedelics supposedly work by desynchronizing the brain

www.nature.com A psychedelic state arises from desynchronized brain activity

Psilocybin induces profound changes in brain connectivity.

A psychedelic state arises from desynchronized brain activity
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  • Yeah no, I'm not too shabby on musical theory.

    Resolve a debate in a separate sub-thread of the comment you replied to.

    When two people play instruments, and they're playing at the same tempo (although this is prolly a simplification), are they not in sync at that point?

    Or would they not?

    No, I'm no musical genius, or even an amateur, it's one of mh worst subjects, musical theory, but it seems to me that if we were to use the analogy of music to psychedelics, I think it would be a bit disingenuous to say the brain desyncs, unless it's in a similar way as with a phase shift in music, but since that sort of still sounds good, wouldn't we be able to argue phase music is still "in sync"?

    Synchronisation has a lot of meanings depending on context. Biology, neurobiology, music, physics, friggin timetables.

    So yeah, your expertise in music is of little use except to improve this analogy. I feel like you can't comment on the original topic as much. Psychedelics and their pharmacology and neuropsychiatric effects.

    I'll be pleased to be proved wrong though.

    • Ok. Based on what? Definitely not that I cultivate and grow psilocybin. Couldn't be that. Nor could it be that I make DMT as well. Definitely wouldn't inform me on this topic at all. Moreover, I'm probably awful at all that music stuff, too. Shit, what could a faceless, nameless stranger on the internet know about anything? Probably not much.

      You win.

      • Based on your very lackluster understanding of their effects.

        "That I make DMT"

        Lol, pretend harder kiddo. Yeah, most organisms do in fact make DMT, but you're talking about EXTRACTING DMT from plant-material which has enough alkaloids for it to be worth it. So what you're pretending to be some arcane drug knowledge is you googling "easiest highs" and trying some of the simpler guides like rice-tek and perhaps an exctraction of either some reeds you collected or a small bag of imported plant material. I'm of the people who wrote those guides.

        You can equivocate all you want, but you're still dodging the fucking question about the subject. No point in trying to pretend to be an expert without any knowledge. It just shows people that you're a pretentious teen.

        • Yep. You're the super-winner now. Got me.

          • Yeah thinking everyone is online "to win" isn't helping with the whole "pretentious teen" part.

            What does it mean when two instruments are playing in sync?

            Can't answer? Oh can, but won't? See before; pretentious teener.

            • Winnnnnnnnn

              • See you're not contributing literally anything, but feel some burning need to reply.

                Because to you, this isn't about conversation. It's about "winnnnnnnnn"

                You can't answer the question. Probably because I'm right about what I said and you can't handle admitting that. Just more immature snarkiness. *Sigh*

41 comments