No problem. I have the opposite problem. A backpack kills my back, but I'm ok with a shoulder bag.

I use a Filson 256 with a Billingham insert to carry two M2s, film, light meter, and an iPad. My MacBook Pro 16" will also fit, but it's a little tight. The Filson 257 has more room and would easily fit it all. It has been discontinued but easy to find used.