Lutris runs games with bunch of stuff like their runtime, dxvk, vkd3d, dxvk-nvapi, dgvoodoo etc
I think checking your lutris settings for what all is enabled and running the game using those may help
Fedora Silverblue
(I made the final switch from Tumbleweed when I discovered that flatpak mpv also has vaapi and the steam and lutris flatpaks work flawlessly)