It's a risky seach if you're squeamish, but Harlequin disease is skin mutation(?) that leads to babies being born with cracked skin and puffy red eyes. The cracks somewhat evoke the patterning of Harlequin's motley attire.
I'd like to thank my designer friend who at a bar told about a thing she was designing, but as someone didn't know the pattern type, somebody did an image search. We never got back to the design talk.