Caves of Qud, our favorite science fantasy roguelike where you can clone, befriend, and eat yourself, is leaving early access in December after 15 years of development
A game which I have started numerous times, and then bounced off of due to the archaic control interface. One of these days I'm going to have to knuckle under and learn how to interact with it, as the concept is cool as hell, and I'm sure the controls become intuitive with practice.
Caves of Qud has gotten more approachable than ever, thanks to a complete UI overhaul, gamepad control implementation, and a currently in-beta tutorial that'll arrive in full with the 1.0 launch.