My preferred way to browse here is using All and blocking communities I don't want to see. That way I get exposed to new things I wouldn't seek out on my own (for example: British archaeology)
I accidentally blocked a community while trying to block a user and when I went to unblock it, I saw I had 1250 communities filtered. If I had to guess, 90% are either porn, sports, or anime.
All things I'm not interested in that tend to fall into these categories:
hyperlocal geographies
sports
specific games
specific hobbies
programming languages and other technologies
porn
meme groups about subcultures I'm not a part of
shitposting
subs where it seems everything is cross posted to another sub
pretty much all music subs (i'm not here for music)
pretty much all video subs (i'm not here for videos)
Edit: I've probably also blocked a handful of obscurely named subs that have no description or shit descriptions. Like a sub called grobslafup and the description is "everything related to grobslafup!" As if people know what the obscure thing is but don't know that a sub titled after it is going to be related to it. 🙄