In the Direct (and other footage) we've seen quite a collection of different weapon types and ways to engage combat. Pistols, rifles, shotguns (and the different ammo types), melee weapons, fists, a couple of shots showed a dev playing primarily with explosives.
What kind of weapons are you planning on using? Often times I try to stick to one/two weapons (depending on the game and skill-system), but I can see myself at least trying out every different kind I find on my first playthrough :D
What about you?
Oh, I just noticed I forgot about space combat - tough I'm not too sure if it makes any difference in gameplay, or if it's more a "use weapon type X to attack their defensive element Y" until you can board/destroy/whatever?