Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients - npj Vaccines
Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients - npj Vaccines
At the start of the COVID-19 pandemic, the BNT162b2 (BioNTech-Pfizer) and mRNA-1273 (Moderna) mRNA vaccines were expediently designed and mass produced. Both vaccines produce the full-length SARS-CoV-2 spike protein for gain of immunity and have greatly reduced mortality and morbidity from SARS-CoV-...
Interesting, from my understanding, in assumedly healthy models, after 48 hours the majority of the mRNA in confined to the injection site, the lymphatic system, and the liver, with it leaving the liver soon after, so its odd seeing correlation of it lasting so long near the heart in those who died from SARS-CoV-2 within 30 days of receiving a vaccine.
I would like to see a follow up study including the hepatic and cardiac fitness of those who died in the same manner. Renal function was a strong factor in recovery, and there's pretty much no doubt about cardiac and hepatic function playing a role as well, but I wonder if these could be just as important and if the presence of vaccine mRNA outside of the injection site or lymph system could be used as reliable indicators for renal and cardiac health, as well as prognosis, in the future.