An electrogenetic interface to program mammalian gene expression by direct current
An electrogenetic interface to program mammalian gene expression by direct current
www.nature.com An electrogenetic interface to program mammalian gene expression by direct current - Nature Metabolism
Huang et al. develop an interface to allow electrode-mediated stimulation of gene expression in human cells, utilizing direct current-generated reactive oxygen species to stimulate transgene expression downstream of the KEAP1–NRF2 biosensor. In a type 1 diabetic mouse model, this interface is demons...
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