As a woman who has hands small enough to wear children's gloves, this love for giant tablet-size phones is so frustrating. I have a pixel 5 and I can't even operate it reliably one-handed. I want a nice camera too, dammit!
Large screens are a problem if you want to use the phone with one hand. There are some apps that would allow you to use the phone with one hand but since I haven't used any I just put a search link where you might find something useful: https://duckduckgo.com/?q=android+app+to+use+phone+with+one+hand
I've mentioned the software solution to my wife, but I think the problem is still that the size/weight of the phone make it difficult to hold and operate one handed even if the pixels are all squished into a corner.