I don't know what you mean, but I do find it silly when a 100lb Harley Quinn is kicking the crap out of 200lb men with guns and riot gear. At least if you get a muscled up woman, it's more believable
Gru is a children's movie character... You may as well reference Jumba Jookiba, who has the coolest evil character arc... Evil alien scientist, has the opportunity to restore his freedom, instead gambles everything on little earth girl. Then decides to stay with little earth girl and become family to her. But does he stop evil experimentation?.. of course not! He is Jumba Jookiba! The most mad evil scientist in the universe. He will make toaster that can only toast Hawaiian toast Mwahah! He will make house that can clean itself to show matriarch of the household that she is unworthy! Jumba will even make a worse version of the thing that got him exiled to the primitive earth planet to begin with! There are no limits to Jumba's depravity, his evil cannot be stopped... except when it comes to helping little earth girl. Or his annoying friend/lover Pleakly.