I did it for a year between Portland, OR and Chicago. You can tell the real cities by not having to specify the state. ;)
I was in my mid to late 20s and really enjoyed doing it at the time, but I don't think I could do it again. 2 weeks there, 1 week home, 2 weeks, 2 weeks, 1 week, 1 week, back and forth back and forth.