Had this happen to me a few days ago and searched for a good while with no fix.
Turns out it a mod-issue with performance fish with large modloads. Go to PF mod options, search for "WorkGiver_DoBillOptimization" and uncheck the 3 boxes beneath it.
You should just need to disable NoMixHelper, not all three. But either way, I believe this issue was fixed recently. Make sure you download the latest version from the GitHub repo or Dubs Discord
You using the version posted on the 8th? I haven't actually played rimworld since before Fish got updated, so if the fix doesn't work then I'm sure Bradson would appreciate a bug report.