Not sure if this is what you mean, but I just finished the first season of Dirk Gently's Holistic Detective Agency, which is filled with SCP themes. I highly recommend the show.
John Dies at the End is also great, although not really an SCP derivative.
Man, the first season of Dirk Gently's was amazing. The second is fine, but a long ways away from the heights of the first. Bummer it never continued, though I seem to remember the show runner did some inappropriate things...
Pretty much doing it's own thing. Other than the titular character and the idea of "everything is connected", there's not much connection to the books.