showerthought: many skincare brands are sadly mostly marketing and no science
But that’s why it’s so nice that there are some gems who actually have scientifically backed formulations, or even better: contribute to science by doing studies and creating new categories!
In regards to safety, yes. They have to make sure you don't develop a rash or something. Good thing there are regulations for that, otherwise at least some companies would try without that, too.
Often those companies just use ingredients and formulations that have been tested on animals by other companies and the patent has run out/it is not patented. Companies doing animal testing probably would not do animal testing on such products too. Most companies try to avoid costs.