What's your favorite game you never hear anybody talk about?
Mine has to be Dragon Quest: Rocket Slime, a DS spin off of the Dragon Quest series that sees you playing as a slime operating a tank and rescuing the people from your town. You run around the overworld, collecting items to use as ammunition and saving money to upgrade your tank. The art and music are just as great as you'd expect from the Dragon Quest series. It made fantastic use of the DS's dual screens. It's also written for a younger audience, so a lot of it is just really silly and fun! Try it out for sure, I'm so sad there's no sequel :(
Rise of Nations. It's like Civilization but as a real-time strategy game and I really enjoy it. Microsoft actually released an updated edition in 2014 which was good of them but I basically never hear anyone actually talk about it which sucks because it's such a cool game. The single-player Conquer the World campaigns are also cool, and have some elements reminiscent of the classic Risk board game.
There's also Star Trek: Bridge Commander, which is often mentioned in discussions of "what Star Trek games were good?" but not much outside of that context. It strikes a perfect balance between having starship combat that really feels like you're commanding a ship with a lot of mass behind it and actually being fun and easy for an average person to pick up and play (which is where stuff like the X Universe games fall down). There are tons of "space fighter" games out there but I've never really seen anything that captures space capital ship combat as well as Bridge Commander.