For guitarists you have either the 100% analog guys that can spend tens of thousands on a collection of amps, or the ones that went more digital with modelers. The big ones being the Kemper, Fractal, Nueral DSP and Line 6. I have the Quad Cortex and it's a killer, thought I wish the rate of updates was a little faster.
I like to split the difference and use one of those nutube amps, I got a voxmv50 AC and it works very well for what I do. Tube purists will stick their noses up, modeling people will gawk at the lack of features, but for someone who doesn't even use reverb or delay it's perfect. (Plus it weighs nothing!)
If it sounds good, I’m into it. I’ve seen really, really expensive amps sound horrible, and relatively cheap ones sound great. But pretty universally, I prefer tubes amps sound.