Dune: Imperium is my current favourite game and i am preparing to teach it on friday, so a couple of solo games have happened this week. Besides that Marvel:United and Karak with my son and the new implementation of Challengers on bga
even though i have not played it with 2, i am certain that is works well with two since i play it solo a lot and that is similar. The game works by emulating the missing players to have 3 using the house haggal deck (i use the dire wolf app, since i find it easier). So a 2 Player game is a 3 player game with 1 automated opponent.
Not yet, i‘ll try to keep my patience until the base game becomes boring, and to me immorality sounds more interesting than ix, but i guess i‘ll have both someday