I used to disable ad blocking on Youtube so creators don't get screwed until Youtube decided to play an ad in the middle of a concert recording. I use both UBlock Origin and AdGuard now, not because I don't care about creators, but because I want the internet to actually be usable. Unintrusive ads are fine, but I don't trust sites to not start with popups and auto-play video ads so they all get blocked.
Adguard doesn't remove all the ad frames or other annoyances that can be nuked with the element picker function of ublock. Thus why they are good complements to each other