Personally, I've been bouncing between several projects like a mink on methamphetamine:
A sword-and-sandal setting for Cepheus Engine, since that ruleset gets lots of Science Fiction love and a lot less for fantasy RPGs.
A pulp SF setting based on ideas from Fritz Leiber's "A Pail of Air" (which I discovered some time ago was in the public domain due to the peculiarities of American copyright law when it was published in 1951).
An "open source" take on a Third Imperium-like setting as a way of giving back to--yet again--the Cepheus Engine community.
This is also besides thinking hard about trying to break out of my comfort zone and write a novel. Two possibilities there....
Needless to say, I'm not actually making much progress on finishing anything.