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I recommend 1g of aspirin and a good bloodletting.
That's for pansies.
You can buy warfarin off the shelf in the form out pest poison.
If you wanna set a world record for death by blood loss, that's the way to do it.
Remember kids:
All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison.
—Paracelsus, 1538
Often condensed to "The dose makes the poison."
Also, death by warfarin overdose is a slow, bloody, painful way to go. Don't self medicate with fucking rat poison or anything stupid.
Was there aspirin in the age of bloodletting?
In the form of willow bark, yes, there was. Salicylic acid, the primary compound in aspirin, is also found in willow bark, which has been used therapeutically for 3500+ years.
https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.14520?sid=nlm%3Apubmed
Nice knowledge! A helluva lot of alcohol was consumed then too, probably even “prescribed” to take with a tincture for whatever the person was suffering from. Willow bark + alcohol + blood letting likely killed more than a few.