I have spent some time in a couple of them, and a possible future career option is actually a transfer to China. It is part of the reason I took the job I have now. I have been studying chinese specifically in case that pans out.
I am sure there would be considerable adjustments, I have lived most of my life in Japan at this point, but I would definitely welcome the opportunity.
I work in hospitality IT, probably not a field I would generally recommend to most people normally but the head regional offices for Asia are located in China.