I've been running "Ledgemancer". Seriously, you can shove so many things. And the things you can't shove can still be displaced by the illithid powers. Plus Larian are such fans of verticality theres always a ledge close by.
Killed the phase-spider matriarch in act 1 with a eldritch blast and because it was dead it was effected by the cantrip and flew off the ledge legitimately wanted to reload that one
Oh yeah you 100% do miss out on loot. I'm doing this in my "Only one party member allowed" playthrough, and it's basically a necessity for killing most bosses if you only have one character at your disposal lol.