It's the scratchpad script where you copy/paste into the about:config console. I just did it for the new v.115 release. I've done it previously but I don't have any set schedule. I guess 1x every six months (2x/year) seems sufficient but I wanted to see what others do.
Yeah, I do that too but every now and then I'll run the cleanup.js script. It always clears away a couple of deprecated prefs. I guess there is no harm in having those older prefs around but clearing them away seems nice.