If the hardware signatures don't match, it wont boot without giving a warning. If the TPM/Secure Enclave is replaced/removed/modified, it will not boot without giving a warning.
If the hardware is tampered, it will not pass the attestation test, which is an online component. It will fail immediately and you will be alerted. Thats the part of verified boot that makes this so much harder for adversaries. They would have to compromise both systems. The attestation system is going to be heavily guarded.